Epigenomics: Regulating the Genome
Epigenomics investigates the chemical modifications and chromatin states that regulate gene activity without altering the DNA sequence. By studying DNA methylation, histone modifications, chromatin accessibility, and regulatory landscapes, epigenomics reveals how cells control identity, development, disease, and environmental response.
What is Epigenomics?
Core Areas
DNA Methylation
Studying chemical marks that influence gene activity and regulation.
Histone Modifications
Understanding chromatin marks that shape gene expression programs.
Chromatin Accessibility
Mapping open and closed chromatin regions that control regulatory activity.
Gene Regulation
Connecting epigenetic states to transcriptional control and cell identity.
Disease Epigenomics
Identifying epigenetic disruptions linked to cancer, aging, and disease risk.
Systems Epigenomics
Integrating epigenomics with transcriptomics, genomics, and multi-omics data.